The reality of racial differences as sold scientific fact (as opposed to liberal delusions that it is a “social construct”) have been confirmed once again by a new study which has shown that an individual’s genetic make-up influences the sort of bacteria found hosting themselves on that person.
The study, “Deep Sequencing Identifies Ethnicity-Specific Bacterial Signatures in the Oral Microbiome” (Mason M, Nagaraja H, Kumar P, et al. PLOS One. 2013) found that oral bacteria are unique to ethnicity.
In a survey of 398 different species of bacteria living underneath the gums of 100 participants representing the four major ethnic groups living in the United States — non-Hispanic blacks, non-Hispanic whites, Chinese, Latinos, the researchers found that only two percent of the species were found living — in different concentrations — within every participant’s mouth.
Eight percent of the same bacterial species were found in 90 percent of their mouths.
“This is the first time it has been shown that ethnicity is a huge component in determining what you carry in your mouth,” study author Purnima Kumar, associate professor of periodontology at The Ohio State University, said in a statement.
“We know that our food and oral hygiene habits determine what bacteria can survive and thrive in our mouths, which is why your dentist stresses brushing and flossing. Can your genetic makeup play a similar role? The answer seems to be yes, it can.”
The researchers then programmed an algorithm into a machine that would be able to classify the DNA signatures of each bacteria.
The machine was able to predict overall ethnicity with 62 percent accuracy.
Breaking it down into specific ethnicities, the machine linked blacks, Latinos, and whites to their particular bacterial communities 100 percent, 67 percent, and 50 percent of the time, respectively.
“This is interesting because although African Americans and Caucasians have shared similar environmental factors including food, nutrition, and lifestyle over several generations — unlike Chinese and Latino subjects who were either immigrants or first generation residents — they demonstrated distinct microbial communities,” the researchers wrote.
This suggests that the individual’s genetic makeup “influences the microbial community to a greater extent than shared environment; ‘nature’ appears to win over ‘nurture’ in shaping this community.”
These differing communities could put certain ethnicities at risk for different kinds of oral disease.
Conversely, they could offer paths for personalized oral care, the researchers wrote.
“ Our data demonstrates that ethnicity exerts a selection pressure on the oral microbiome, and that this selection pressure is genetic rather than environmental, since the two ethnicities that shared a common food, nutritional and lifestyle heritage (Caucasians and African Americans) demonstrated significant microbial divergence.
“It is known that tooth and root morphologies vary according to ethnic affiliation, as do innate immune responses to infectious agents, for example, Toll-like receptor-4, mannose binding lectin and heat-shock proteins, and it is possible that ethnicity plays a role in bacterial selection by defining the environment for bacterial colonization.
“The concept that the host genotype chooses what will survive and thrive is particularly important in assessing susceptibility and in developing targeted therapies to combat polymicrobial infections. For example, pathogens belonging to the genera Filifactor, Staphylococcus, Mycoplasma, and Treponema were found in significantly higher levels in Chinese and Latinos, and it is possible that their presence in health may contribute to the increased disease susceptibility that has been observed in these cohorts .
“ Successful treatment of biofilm-associated diseases requires re-establishing healthy oral biofilms, and current treatment protocols assume that the composition of health-compatible biofilms are similar among all populations. The data presented here suggest that the health-compatible communities consist of significantly different types of species as well as different ratios of common species between different ethnicities and therefore, microbial replacement therapy has to be tailored to cohorts rather than be universally applied.
“In summary, the work presented here demonstrates the existence of ethnicity-specific subgingival microbiomes that are characterized by differing bacterial lineages and varying diversities. It is possible that these health-associated ethnicity-specific microbial communities may predispose individuals to future disease and warrants further examination.”